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生物样品前处理技术与产品的开发

发布时间:2019-07-11   浏览次数:0

蒋晔,教授,药学院博士生导师,主要研究方向为:复杂基质样品分析及样品前处理技术

课题组在复杂基质生物样品前处理研究方面处于世界领先地位,其开发的中空纤维离心超滤技术(HFCF-UF)具有独立的自主知识产权,HFCF-UF在中药分析、食品检验、临床检验、药物及其制剂分析及生物样品分析等方面有着广泛应用,特别是在游离药物浓度分析方面处于世界领先地位。HFCF-UF不仅可以用于游离药物浓度分析,在临床检验生物安全主动防护方面上具有较好的应用前景。课题组在其它新型样品前处理技术的研究方面如液液微萃取、顶空分析技术、离子液体样品前处理等方面的研究在国内、国际均处于领先的地位。近3年来以通讯作者发表SCI论文多篇:

1.Mengjiao Li,Haiyan Ma,Jinglin Gao,Lina Zhang,Xinyu Wang,Di Liu,Jing Bian,Ye Jiang*. Rapid screening of non-steroidal anti-inflammatory drugs illegally added in anti-rheumatic herbal supplements and herbal remedies by portable ion mobility spectrometry[J]. Journal of Pharmaceutical and Biomedical Analysis,2017,145.  IF:3.05

2.Gao J L , Wang X Y , An J , et al. The significance of a new parameter ?C plasma protein binding ?C in therapeutic drug monitoring and its application to carbamazepine in epileptic patients[J]. RSC Adv. 2017, 7(45):28048-28055.   IF:3.01

3.Congcong Ran,Dan Chen,Meng Xu,Chaohui Du,Qinglian Li,Ye Jiang*. A study on characteristic of different sample pretreatment methods to evaluate the entrapment efficiency of liposomes[J]. Journal of Chromatography B,2016,1028.  IF:2.57

4.Congcong Ran,Dan Chen,Haiyan Ma,Ye Jiang*. Graphene oxide adsorbent based dispersive solid phase extraction coupled with multi-pretreatment clean-up for analysis of trace aflatoxins in traditional proprietary Chinese medicines[J]. Journal of Chromatography B,2017. IF:2.57

5.]Ma,Ran,Li,Gao,Wang,Zhang,Bian,Li,Jiang*. Graphene oxide-coated stir bar sorptive extraction of trace aflatoxins from soy milk followed by high performance liquid chromatography-laser-induced fluorescence detection[J]. Food Additives & Contaminants: Part A,2018,35(4).  IF:2.129

6.Wang X , Gao J , Du C , et al. A novel pretreatment method combining sealing technique with direct injection technique applied for improving biosafety[J]. Bioanalysis, 2016, 9(2):173. IF:1.86